Showing 10 results of 49 tagged “Molecular Genetics and Microbiology”.

An overlay of six X-ray crystal structures of DNA shows that regular (Watson-Crick) and mismatched DNA are similarly bent by the transcription factor TBP. However, the mismatched DNA is highly preferred by the protein because it is easier to distort.

Transcription Factors May Inadvertently Lock in DNA Mistakes

Binding to mismatched DNA takes less energy; may explain how regulatory mutations get locked in

DURHAM, N.C. -- Transcription factor proteins are the light switches of the human genome. By...

At home experimental set-up and data collection in the author's apartment.

Why Wednesday Is the Favorite Day for This Undergraduate Science Student

Or if something has fundamentally shifted in our institution, and more largely in each of us individually, that only leaves us with a path forward to a new Duke, rather than a return to the old.

When malaria fevers hit, the parasites in a person’s blood use a clever trick to take the heat. Credit: Pixabay

Duke Researchers Discover How Malaria Parasites Withstand a Fever’s Heat

Findings could lead to ways to maximize our existing antimalarial arsenal

DURHAM, N.C. -- Even when a person suffering from malaria is burning up with fever and too sick...

Fourteen days after infection with an influenza B virus, cells of a mouse nose are colored to show any remaining infection. Red cells were infected but have now cleared the virus. (Sebastian Wellford)

Scent-Sensing Cells Have a Better Way to Fight Flu

Olfactory neurons can fight off influenza B without being killed

DURHAM, N.C. – Influenza researchers have long focused most of their efforts on the...

Everybody's Microbiome Is Different. So How Do You Study It Usefully?

Unusual Immune Response in Bladder Appears to Drive Repeat UTIs

Lab Research Analyst Samantha Skavicus works n the lab of Nicholas Heaton. Photo courtesy of Nicholas Heaton.

Duke Labs Begin Phased, Deliberate March Toward Reopening

With plenty of safeguards and patience, some research resumes in pockets on campus

On most days, Stacy Horner does her work in the CARL Building, where corridors and labs are...

Duke Scientists Studying the Shape of COVID Things to Come

New members of the AAAS: Clockwise from top left: Rachel Kranton, Fan Wang, Richard Mooney, Vincent Price, Sally Kornbluth, Joseph Heitman, Blanche Capel and Geri Dawson.

Price, Kornbluth and Six Senior Faculty Join American Academy of Arts & Sciences

President Vincent Price, Provost Sally Kornbluth and six other Duke faculty members have been...

Genetic samples from developmentally disabled children have identified dozens of new mutations in the DDX3X gene that lead to smaller brains and intellectual disability because of the gene’s role in neuron genesis and transport. Credit: Silver Lab.

Duke-Led Study Catalogs Dozens of Mutations in Crucial Brain Development Gene

Brain growth gene’s malfunction can now be considered a developmental disability syndrome

An international team of researchers that pooled genetic samples from developmentally disabled...